Protein Modification Reagents
![eMolecules DOPE-PEG-Fluor 488, MW 2,000 | Broadpharm |1369.560 | C65H94N4NaO20PS2 | 98.000 | [Na+].CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCCNC(=O)OCCNC(=O)c1ccc(c(c1)C(O)=O)-c1c2ccc(N)c(c2oc2c(c(=[NH2+])ccc12)S([O-])(=O)=O)S(O)(=O)=O)OC(=O)CCCCCCC\C=C/CCCCCCCC | 1mg | 798870839](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502508684.JPG-250.jpg)
eMolecules DOPE-PEG-Fluor 488, MW 2,000 | Broadpharm |1369.560 | C65H94N4NaO20PS2 | 98.000 | [Na+].CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCCNC(=O)OCCNC(=O)c1ccc(c(c1)C(O)=O)-c1c2ccc(N)c(c2oc2c(c(=[NH2+])ccc12)S([O-])(=O)=O)S(O)(=O)=O)OC(=O)CCCCCCC\C=C/CCCCCCCC | 1mg | 798870839
DOPE-PEG-Fluor 488, MW 2,000 | Broadpharm |1369.560 | C65H94N4NaO20PS2 | 98.000 | [Na+].CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCCNC(=O)OCCNC(=O)c1ccc(c(c1)C(O)=O)-c1c2ccc(N)c(c2oc2c(c(=[NH2+])ccc12)S([O-])(=O)=O)S(O)(=O)=O)OC(=O)CCCCCCC\C=C/CCCCCCCC | 1mg | 798870839
Medchemexpress LLC PROTAC STING degrader-3 | 3109967-69-0 | 98.0% | 752.73 | 1 MG
PROTAC STING degrader-3 is a STING PROTAC degrader that induces STING degradation via the ubiquitin-proteoteasome pathway. It exerts anti-inflammatory effects by inhibiting STING/TBK1/NF-κB signaling and has renal protective effects, making it useful in the study of acute kidney injury (AKI).
- STING ligand
- Cereblon ligand
- Linker
Medchemexpress LLC DSPE-PEG3-azide | 97.0% | 977.30 | 100 MG
DSPE-PEG3-azide (DSPE-PEG3-N3) is an azide containing lipid that can be used to form micelles as nanoparticles for drug delivery. It is a click chemistry reagent that contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Can be used to form micelles as nanoparticles for drug delivery.
- Contains an azide group.
- Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with alkyne groups.
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups.
Vector Laboratories VECTOR LABORATORIES LLC TCO-PEG3-Maleimide, MW 523.62, Purity >95%
TCO-PEG3-Maleimide enables simple and efficient incorporation of TCO moiety onto antibodies, cysteine-containing peptides and other thiol-containing molecules. The maleimide group specifically and efficiently reacts with reduced thiols (sulfhydryl groups, –SH) at pH 6.5 to 7.5 to form stable thioether bonds. The hydrophilic polyethylene glycol (PEG) spacer arm improves solubility in aqueous buffers.
- CAS number: 1609659-01-9
- Molecular weight: 523.62
- Molecular formula: C26H41N3O8
- Appearance: Colorless to slightly yellow oil
- Purity: >95% (HPLC)
- Solubility: DMSO, DMF, DCM, THF, Chloroform
- Storage instructions: −50°C to −85°C
- Shipping conditions: Dry ice
- For research use only.
Medchemexpress LLC HY-W008474 100mg Medchemexpress, PROTAC Linker 13 CAS:153086-78-3 Purity:>98%
Medchemexpress, HY-W008474 100mg PROTAC Linker 13 CAS:153086-78-3 PROTAC Linker 13 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 13 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
![eMolecules N-(Azido-PEG2)-N-PEG4-t-butyl ester | Broadpharm |478.587 | C21H42N4O8 | 90.000 | CC(C)(C)OC(=O)CCOCCOCCOCCOCCNCCOCCOCCN=[N+]=[N-] | 500mg | 591908394](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502183640.JPG-250.jpg)
eMolecules N-(Azido-PEG2)-N-PEG4-t-butyl ester | Broadpharm |478.587 | C21H42N4O8 | 90.000 | CC(C)(C)OC(=O)CCOCCOCCOCCOCCNCCOCCOCCN=[N+]=[N-] | 500mg | 591908394
N-(Azido-PEG2)-N-PEG4-t-butyl ester | Broadpharm |478.587 | C21H42N4O8 | 90.000 | CC(C)(C)OC(=O)CCOCCOCCOCCOCCNCCOCCOCCN=[N+]=[N-] | 500mg | 591908394
STA PHARMACEUTICAL US LLC Fmoc-NH-PEG20-CH2CH2COOH | 10 g | CAS 1952360-93-8 | MDL MFCD21363316
Fmoc-NH-PEG20-CH2CH2COOH is a Amino Acid reagent (Subcategory: PEG AA) sold by WuXi TIDES. Offered in 10 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 1952360-93-8
- MDL: MFCD21363316
- InChIKey: YIKBHNBKAGGRHQ-UHFFFAOYSA-N
- Molecular Weight: 1192.397
- Molecular Formula: C58H97NO24
- Purity: ≥95%
- Container Type: 60 mL HDPE
- Pack Size: 10 g
- Net Weight: 10 g
- Gross Weight: 25 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55,58,61,64-henicosaoxa-4-azaheptahexacontan-67-oic acid
- SMILES: O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(OCC1C2=C(C=CC=C2)C3=C1C=CC=C3)=O)O
Medchemexpress LLC Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD | 1037589-69-7 | 99.8% | 528.55 | 25 MG
Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD (Mal-PEG2-AZD) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. It is for research use only.
- Used in the synthesis of PROTACs.
- Exploits the intracellular ubiquitin-proteasome system.
- Selectively degrades target proteins.
- For research use only.
Medchemexpress LLC Dbco-peg24-nhs ester | 2765066-38-2 | C74H119N3O30 | 5 MG
DBCO-PEG24-NHS ester is a click chemistry reagent that reacts specifically and efficiently with primary amines at neutral or slightly basic conditions to form a covalent bond. DBCO is commonly used for copper-free Click Chemistry reactions. It is for research use only.
- The hydrophilic PEG spacer arm improves water solubility
- Provides a long and flexible connection that minimizes steric hindrance involved with ligation
eMolecules 2250216-94-3 | t-Boc-Aminooxy-PEG5-amine | Broadpharm396.481 | C17H36N2O8 | 98.000 | CC(C)(C)OC(=O)NOCCOCCOCCOCCOCCOCCN | 500mg | 550804543
t-Boc-Aminooxy-PEG5-amine | Broadpharm | 2250216-94-3396.481 | C17H36N2O8 | 98.000 | CC(C)(C)OC(=O)NOCCOCCOCCOCCOCCOCCN | 500mg | 550804543
Broadpharm Bromo-PEG3-CH2CO2tBu | 2100306-71-4 | MFCD30723231 | 500mg
Bromo-PEG3-CH2CO2tBu | Putity: 98% | MW: 327.2 | 2100306-71-4 | MFCD30723231 | 500mg
STA PHARMACEUTICAL US LLC Fmoc-NH-PEG6-CH2CH2COOH | 100 g | CAS 882847-34-9 | MDL MFCD06656474
Fmoc-NH-PEG6-CH2CH2COOH is a Amino Acid reagent (Subcategory: PEG AA) sold by WuXi TIDES. Offered in 100 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 882847-34-9
- MDL: MFCD06656474
- InChIKey: HEGZERUHBVYZPH-UHFFFAOYSA-N
- Molecular Weight: 575.655
- Molecular Formula: C30H41NO10
- Purity: ≥95%
- Container Type: 500 mL HDPE
- Pack Size: 100 g
- Net Weight: 100 g
- Gross Weight: 160.5 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22-heptaoxa-4-azapentacosan-25-oic acid
- SMILES: O=C(CCOCCOCCOCCOCCOCCOCCNC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)O
